李妍妍 副教授 硕士生导师

研究方向

1. 纳米药物递送系统

2. 多功能诊疗制剂

3. 纳米植物药

联系方式：liyanyan@nefu.edu.cn

学习及工作经历

2017/07 -至今      东北林业大学    专业：生药学                     副教授

2010/09 -2017/04   哈尔滨工业大学  专业：生物医学工程               工学博士

2008/07 -2010/07   吉林大学        专业：生物化学与分子生物学专业   理学硕士

2006/03 -2008/01   东北林业大学    专业：英语专业（第二专业）       文学学士

2004/09 -2008/07   东北林业大学    专业：动物医学专业               农学学士

研究经历

2017/07-至今      东北林业大学     活性药物缓控释、多功能诊疗制剂，纳米中药

2012/11-2015/12   北京大学         siRNA递送载体、多功能诊疗探针的制备

2010/07-2017/04   哈尔滨工业大学   药物递送载体、多模态诊疗探针的研究

2008/09-2010/07   吉林大学         内源性逆转录病毒与脊髓侧索硬化症的相关性研究

2004/09-2008/07   东北林业大学     COI基因用于马鹿和梅花鹿物种识别初探

2006/03-2007/12   东北林业大学     分子生物学文献中专业词汇翻译的探究

代表论文

1.      Yanyan Li, Yidi Wu, Shuquan Zheng, Xiaolong Liang, Xiaorui Han, Renfa Liu, Deyao Zhao,Yunhui Zhao, Yushen Jin, Min Chen, Xiaoxia Wang, Huiqing Cao, Xiuli Yue*, Tiejun Sten Shi*,Zicai Liang**. PEGylated Cationic Hybrid Bicellar Nanodisc for Efficient siRNA Delivery, RSC Advances, 2016,6(114), 113745-113753 (IF 3.289,Q2)

2.      Xiaolong Liang, Yanyan Li, Zhifei Dai*,PEGylated Polypyrrole Nanoparticles Conjugating Gadolinium Chelates for Dual-Modal MRI/Photoacoustic Imaging Guided Photothermal Therapy of Cancer. Advanced Functional Materials, 2015, 25(9), 1451–1462. (Co-first author)  (IF 11.328，Q1)

3.      Yanyan Li, Shuquan Zheng, Xiaolong Liang, Yushen Jin, Yidi Wu, Huichen Bai, Renfa Liu, Zhifei Dai*, Zicai Liang*, Tiejun Shi, Doping Hydroxylated Cationic Lipid into PEGylated Cerasome boosts In vivo siRNA Transfection Efficacy. Bioconjugate Chemistry, 2014, 25(11), 2055–2066. (IF 4.5, Q1)

4.      Yushen Jin, Yanyan Li, Xibo Ma, Zhengbao Zha, Liangliang Shi, Jie Tian, Zhifei Dai*, Encapsulating Tantalum Oxide into Polypyrrole Nanoparticles for X-ray CT/Photoacoustic Bimodal Imaging-Guided Photothermal Ablation of Cancer, Biomaterials, 2014, 35, 5795-5804.  (IF 8.387，Q1)

5.      Yushen Jin, Yanyan Li, Hongjie Pan, Zhifei Dai*, Liposomal nanohybrid cerasomes for controlled insulin release, RSC Advances, 2014, 4, 42808-42815. (IF 3.289，Q2)

6.      Yushen Jin, Hongjie Pan, Yanyan Li, Zhifei Dai*, Chitosan modified cerasomes incorporating poly (vinyl pyrrolidone) for oral insulin delivery, RSC Advances, 2014, 4, 58137-58144.  (IF 3.289，Q2)

7.      Guanglei Fu, Wei Liu, Yanyan Li, Yushen Jin, Lingdong Jiang, Xiaolong Liang, Shanshan Feng, Zhifei Dai*, Magnetic Prussian Blue Nanoparticles for Targeted Photothermal Therapy under Magnetic Resonance Imaging Guidance, Bioconjugate Chemistry, 2014, 25 (9), 1655–1663.  (IF 4.5, Q1)

8.      Zhengbao Zha, Zijian Deng, Yanyan Li, Changhui Li, Jinrui Wang, Shumin Wang, Enze Qu, Zhifei Dai*, Biocompatible polypyrrole nanoparticles as a novel organic photoacoustic contrast agent for deep tissue imaging, Nanoscale, 2013,5, 4462-4467.  (IF 7.76，Q1)

9.      Zhengbao Zha, Shuhai Zhang, Zijian Deng, Yanyan Li, Changhui Li, Zhifei Dai*, Enzyme-responsive copper sulphide nanoparticles for combined photoacoustic imaging, tumor-selective chemotherapy and photothermal therapy, Chem. Commun., 2013,49, 3455-3457. (IF 6.67，Q1)