盖庆岩副教授,女,1989年10月出生,黑龙江省肇东市人,硕士研究生导师,东北林业大学“优秀青年学者”高层次引进人才,主要从事药用植物次生代谢产物代谢调控机制研究。近五年以第一作者身份发表SCI论文7篇,在中科院1区TOP级期刊发表论文4篇;近五年先后参加及主持国家和省部级项目8项;曾获梁希林业科学技术奖二等奖、梁希优秀学子奖、梁希青年论文奖一等奖等。
学习与工作经历:
2007.09-2011.07 东北林业大学,生物技术,学士;
2011.09-2014.06 东北林业大学,生药学,硕士;
2014.09-2017.06 东北林业大学,植物学,博士;
2017.07-至今 东北林业大学,森林植物生态学教育部重点实验室,植物学,副教授。
科学研究方向:
盖庆岩副教授主要从事药用植物生物技术及次生代谢产物生物合成调控机制研究,主要包括药用植物毛状根培养技术、药用植物细胞悬浮培养技术及参与次生代谢产物生物合成的关键酶基因的筛选等内容。
近年主要研究课题:
1.中央高校基本科研业务费专项资金项目,2572017ET03,典型林源活性成分加工利用关键技术,2017/10-2020/10,55万元,在研,参加;
2.黑龙江省青年科学基金项目,QC2017012,黄芪皂苷生物合成相关CYP450酶基因的筛选及功能研究,2017/10-2020/10,5万元,在研,参加;
3.国家重点研发计划,2017YFD06013060104,红豆杉茎段腋芽增殖培育技术研究,2017/07-2020/12,20万元,在研,主持;
4.横向课题,2017-145,桦褐孔菌生物活性物质基础、作用机制及新产品开发,2017/06-2019/07,10万元,在研,主持;
5.中央高校基本科研业务费专项资金项目,2572015AA14,板蓝根中苯丙素类化合物生物合成途径的关键酶调控机制研究,2015/03-2017/03,3万元,已结题,主持;
6.中央高校基本科研业务费专项资金项目,2572015EA04,东北特色浆果资源精深加工利用技术研究,2015/01-2018/12,40万元,已结题,参加;
7.中央高校基本科研业务费专项资金项目,2572014AA06,CYP450s和GTs酶在黄芪皂苷生物合成中的功能研究,2014/03-2016/02,3万元,已结题,参加;
8.哈尔滨市应用技术研究与开发项目,2013AA3BS014,木豆叶提取物及其单体成分抗动脉粥样硬化斑块新药研发,2012/04-2014/04,100万元,已结题,参加。
近年主要发表论著:
1. Qing-Yan Gai, Jiao Jiao, Meng Luo, Wei Wang, Li-Ping Yao, Yu-Jie Fu*. Deacetylation biocatalysis and elicitation by immobilized Penicillium canescens in Astragalus membranaceus hairy root cultures: towards the enhanced and sustainable production of astragaloside IV. Plant Biotechnology Journal, 2017 (IF=7.443, 植物科学1区);
2. Qing-Yan Gai, Jiao Jiao, Meng Luo, Wei Wang, Chun-Jian Zhao, Yu-Jie Fu*, Wei Ma. UV elicitation for promoting astragaloside production in Astragalus membranaceus hairy root cultures with transcriptional expression of biosynthetic genes. Industrial Crops and Products, 2016(IF=3.181, 农林科学1区);
3. Qing-Yan Gai, Jiao Jiao, Fu-Yao Wei, Meng Luo, Wei Wang, Yuan-Gang Zu, Yu-Jie Fu*. Enzyme-assisted aqueous extraction of oil from Forsythia suspense seed and its physicochemical property and antioxidant activity. Industrial Crops and Products, 2013 (IF=3.181, 农林科学1区);
4. Qing-Yan Gai, Jiao Jiao, Pan-Song Mu, Wei Wang, Meng Luo, Chun-Ying Li, Yuan-Gang Zu, Fu-Yao Wei, Yu-Jie Fu*. Microwave-assisted aqueous enzymatic extraction of oil from Isatis indigotica seeds and its evaluation of physicochemical properties, fatty acid compositions and antioxidant activities. Industrial Crops and Products, 2013 (IF=3.181, 农林科学1区);
5. Qing-Yan Gai, Jiao Jiao, Meng Luo, Wei Wang, Wei Ma, Yuan-Gang Zu, Yu-Jie Fu*. Establishment of high-productive Isatis tinctoria L. hairy root cultures: A promising approach for efficient production of bioactive alkaloids. Biochemical Engineering Journal, 2015 (IF=2.892, 工程技术2区);
6. Qing-Yan Gai, Jiao Jiao, Meng Luo, Zuo-Fu Wei, Yuan-Gang Zu, Wei Ma, Yu-Jie Fu*. Establishment of hairy root cultures by Agrobacterium rhizogenes mediated transformation of Isatis tinctoria L. for the efficient production of flavonoids and evaluation of antioxidant activities. PloS one, 2015 (IF=2.806, 生物3区);
7. Qing-Yan Gai, Jiao Jiao, Meng Luo, Wei Wang Cheng-Bo Gu, Yu-Jie Fu*, Wei Ma. Tremendous enhancements of isoflavonoid biosynthesis, associated gene expression and antioxidant capacity in Astragalus membranaceus hairy root cultures elicited by methyl jasmonate. Process Biochemistry, 2016 (IF=2.497, 生物3区);
所获科研奖励:
1.木豆资源功能活性成分高值化加工利用关键技术及产业化应用,梁希林业科学技术奖,二等奖,第7完成人;
2. Enzyme-assisted aqueous extraction of oil from Forsythia suspense seed and its physicochemical property and antioxidant activity,第六届梁希青年论文奖,一等奖。
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